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Yeast Metabolic Engineering: Methods And Protocols (methods In Molecular Biology)

Yeast Metabolic Engineering: Methods and Protocols provides the widely established basic tools used in yeast metabolic engineering, while describing in deeper detail novel and innovative methods that have valuable potential to improve metabolic engineering strategies in industrial biotechnology applications. Beginning with an extensive section on molecular tools and technology for yeast engineering, this detailed volume is not limite...

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The Molecular Pathology Of Autoimmune Diseases

Remarkable advances have been made in the pathogenesis of autoimmunity, such as with bone marrow transplantation, which is becoming a powerful strategy in treating certain life-threatening diseases. The Molecular Pathology of Autoimmune Diseases is a concise and centralized resource for information on the topic, with a special focus on the molecular and genetic basis of these disorders. Dozens of international experts devote themselv...

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Talens: Methods And Protocols

This volume provides a comprehensive collection of protocols on new technology across various model organisms.  Chapters describe species-specific methods to generate new mutants the content is completed by chapters on natural TAL effectors, TAL element DNA binding principles, TALEN target site prediction, and methods for the efficient construction of TALEN coding regions. While addition chapter focus on the application of TALEN as s...

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Drosophila Oogenesis: Methods And Protocols

This volume provides current up-to-date protocols for preparing the ovary for various imaging techniques, genetic protocols for generating mutant clones, mosaic analysis and assessing cell death. Chapters address methods for performing genome wide gene expression analysis and bioinformatics for studies of RNA-protein interactions. Written in the highly successful Methods in Molecular Biology series format, chapters include introducti...

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Physiology, Volume 4: The Natural History Of The Crustacea

The Crustacea is one of the dominant invertebrate groups, displaying staggering diversity in form and function, and spanning the full spectrum of Earth's environments. Crustaceans are increasingly used as model organisms in all fields of biology, as few other taxa exhibit such a variety of body shapes and adaptations to particular habitats and environmental conditions. Physiological Regulation is the fourth volume in The Natural Hist...

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In Search Of Mechanisms: Discoveries Across The Life Sciences

Neuroscientists investigate the mechanisms of spatial memory. Molecular biologists study the mechanisms of protein synthesis and the myriad mechanisms of gene regulation. Ecologists study nutrient cycling mechanisms and their devastating imbalances in estuaries such as the Chesapeake Bay. In fact, much of biology and its history involves biologists constructing, evaluating, and revising their understanding of mechanisms. With In Sear...

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Drinking Water And Infectious Disease: Establishing The Links

In many countries, considerable uncertainty still exists about the contribution of drinking water to sporadic cases of disease. The Organization for Economic Cooperation and Development (OECD), in cooperation with the World Health Organization (WHO), led the Workshop on Molecular Technologies for Safe Drinking Water in 1998 to address the role of water in the transmission of infectious disease. One of the results was a call for impro...

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Biotechnology And Bioinformatics – Advances And Applications For Bioenergy, Bioremediation And Biopharmaceutical…

Reflecting the interdisciplinary nature of biotechnology, this book covers the role of targeted delivery of polymeric nanodrugs to cancer cells, microbial detoxifying enzymes in bioremediation and bacterial plasmids in antimicrobial resistance. It addresses modern trends such as pharmacogenomics, evaluation of gene expression, recombinant proteins from methylotrophic yeast, identification of novel fermentation inhibitors of bioethano...

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Bacterial Membranes: Structural And Molecular Biology

Membranes are pivotal components of life, acting as formidable insulators that demarcate a living cell; generate energy in the form of ion gradients; transport ions, proteins, nucleic acids, nutrients, and metabolites; and provide transduction systems to sense the environment and to communicate with other cells. Membranes also provide shape and structure to cells and are important in cell motility. In addition, they fulfill a scaffol...

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Fins Into Limbs: Evolution, Development, And Transformation

Long ago, fish fins evolved into the limbs of land vertebrates and tetrapods. During this transition, some elements of the fin were carried over while new features developed. Lizard limbs, bird wings, and human arms and legs are therefore all evolutionary modifications of the original tetrapod limb. A comprehensive look at the current state of research on fin and limb evolution and development, this volume addresses a wide range of s...