Oncogene-Induced Senescence: Methods and Protocols

41Lh1LZkYGL._SY291_BO1,204,203,200_QL40_ Author Mikhail A Nikiforov
Isbn 9781493966684
File size 7MB
Year 2016
Pages 220
Language English
File format PDF
Category Biology

Book Description:

This book offers in a single volume a unique collection of the state-of the-art experimental procedures utilized for the induction, detection, and modeling of this complex cellular program of oncogene-induced senescence. The book encompasses protocols for studying this multi-step program in human specimens and a variety of experimental models including cultured mammalian cells, laboratory mice, andDrosophila melanogaster, as well as offering a description of high throughput approaches. Written for the highly successfulMethods in Molecular Biologyseries, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Authoritative and practical,Oncogene-Induced Senescence: Methods and Protocolsrepresents a valuable asset for a wide audience of medical oncologists and researchers in the fields of oncology, molecular and cellular biology, biochemistry, and animal development.

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